Showing posts with label carcinoma. Show all posts
Showing posts with label carcinoma. Show all posts

Friday, November 13, 2009

Lung cancer - I - Intro

Lung cancer is a serious, high risk disease. There are many important things to be said about this disease, so we will structure this article into more chapters. This one is the first one.

Lung cancer, like all cancers, result from an anomaly in the fundamental unit of life cell. Normally the body maintains a system of checks and balances on economic growth in cells such as cells divide to produce new cells only when necessary. Disorders of this system of checks and balances result in an increase in cell division and uncontrolled proliferation of cells that eventually forms a mass known as tumor.

Benign tumors can usually be removed and not spread to other parts of the body. Malignant tumors, on the other hand, grow aggressively and invade other tissues of the body, which allows entry of tumor cells in the blood or lymphatic system and then to other organs. This spread is called metastasis; tumor growth areas in these organs are called metastases. Since lung cancer tends to spread or develop metastases very early, we can say that is a serious form of cancer, high risk and it is also difficult to treat.

While lung cancer can spread to any organ in the body, certain organs - particularly the adrenal glands, liver, brain, bones are the organs most commonly affected, with a high risk of developing metastases. Metastasis tumor is composed of the same type of cells as the original tumor. For example, prostate cancer, if it spreads through the blood to the lungs, talk about prostate cancer in lung cancer, not lung cancer.

The main function of the lungs is gas exchange between blood and the air we breathe. The work of the lungs, carbon dioxide is removed from the blood and the inspired oxygen enters the bloodstream. Right lung has three lobes, whereas left lung is divided into two lobes and a smaller structure called the lingula which is equivalent to the middle lobe. Major airways into the lungs are the bronchi, resulting in the trachea. Bronchi branch into progressively smaller airways called bronchiole. They end in small bags known as pulmonary alveoli. The wafers are exchanged gas itself. Lungs and chest wall are covered with a thin layer of tissue called pleura.

Various types of lung cancer can occur in any part of the lung, but 90% -95% of lung cancer cases are believed to originate from epithelial tissues, or cells lining the respiratory tract and older children (bronchi and bronhiolele), for this reason, forms of cancer are bronhogenics sometimes called carcinoma or bronchogenic cancers. Cancers can arise also from the pleura (thin layers of tissue surrounding the lungs) or, rarely, from blood vessels.

Lung cancer is the most common cause of death among people with cancer. According to the U.S. National Cancer Institute, about 1 in 14 people in USA will contact disease during their life.
Lung cancer generally occurs in older age, 70% of those affected with over 65 years, only 3% of cases occur in people under 45 years.
Pulmonary cancer was a relatively rare disease before 1930, but the number of cases increased rapidly with the increasing number of smokers, and developing industrialization.
Lately however is noted a slight decrease in the number of cases due to awareness of the negative role of smoking and quitting the habit and also because anti-tobacco campaigns.
However, lung cancer remains the leading cause of death among females; the number of deaths exceeded the number of deaths due to breast cancer.


(To be continued)


Sunday, November 1, 2009

About Neuro-endocrine Carcinoma

One of many forms of cancer is aggressive and devastating neuro-endocrine carcinoma of the colon. The worst feature of this disease is that it is usually detected in advanced stages, at which it is often difficult to treat.

Neuroendocrine colon cancer symptoms become visible only in the advanced stages, so the patient survival rate diminishes. Malignant tumors are mostly detected with remote metastases. Most recent studies show that in almost all cases of neuroendocrine cancer patient's death occurs.

Research findings are pessimistic, the final results of this type of cancer are the same, regardless of age or sex of sick person or location of the tumor. Although neuroendocrine carcinoma of the colon depends on the stage where the tumor, generally patients in stages 1 and 2 of the disease do not suffer from this type of colon cancer (neuroendocrine). In most cases where the tumor is in stage 3 or 4, is very difficult to determine if it is this form of cancer.

Unfortunately, medical science failed to develop any appropriate method to deal with this particular type of cancer. A technique that could use the method of immunohistochemical staining. This method helps doctors to determine the severity of colon cancer and helps determine neuroendocrine useful drug for treating and improving it. Colorarii immunohistochemical method is used specifically for neuroendocrine markers. This involves staining tumor with a monoclonal antibody-80, which will help identify the quantum of neuroendocrine differentiation and the nature of damage to the health of patients.

Unfortunately, neuroendocrine cancer of the colon has a good prognosis and surgery is often powerless against this disease.
For these reasons it is necessary to monitor population health status, so as to take appropriate measures since the first symptoms of illness.

More info HERE